1601006067 - Final Year Practical Long Case

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A 50 year old female home maker resident of Nalgonda , came to OPD with chief complaints of 

1. Pain

2. Stiffness in several joints since 3 months

History of presenting illness :

- Patient was apparently asymptomatic 10 years ago , then she developed a dull aching type of pain & stiffness in her metacarpophalangeal joints in her right hand which is associated with limitation of movements at the joint

- Then within 6 months of onset , it progressed to involve other joints of the right & left hand as well as wrist & elbow joint

- Then within 4 years of onset , she started feeling pain in the joints of feet & ankle

- Since 3 months the pain became unbearable which limited her activities

- PAIN was insidious in onset , slowly progressive , dull aching type , non radiating , associated with swelling & stiffness of the involved joint

- Stifness & Pain were more in the morning & gradually improved with movements

- No deformities 

- No loss of weight

Past History :

- No similar complaints 10 years ago

- No history of Diabetes , Hypertension , TB , Asthma , Epilepsy , Thyroid

Drug History :

- No known drug allergies

Menstrual History :

- Age of Menarche at 13 years

- Regular cycles , 4/28 , No Pain , No clots

- Age of Menopause at 47 years 

Family History :

- No significant family history

Personal History :

- Mixed Diet

- Normal Appetite

- Regular Bowel & Bladder movements 

- Adequate Sleep

- No Addictions

General Examination :

- Patient consent was obtained

- Patient was Conscious , Coherent , Cooperative , Moderate Built & Nourished

- No Pallor , Icterus , Cyanosis , Clubbing , Lymphadenopathy , Edema

VITALS -

Temperature : Afebrile
Blood Pressure : 120 / 70 mmHg in right arm sitting position 
Pulse : 80 beats / min , regular rhythm , normal volume & character 
Respiratory Rate : 15 cycles / min

Local Examination :

INSPECTION :

- Swelling over the metacarpophalengeal joints in both hands
- No Subcutaneous nodules
- No pigmentation 
- No scars
- No atrophic changes
- No purpura
- No ulcerations
- No gangrene
- No nail changes
- No deformities in hands & feet



PALPATION :

- Skin is warm
- Sensations are present
- Mild Swelling over the joint capsule
- Tenderness over the joint is present
- Decreased range Movements at PIP , MCP , Wrist , Elbow & Ankle joints
- All active & passive movements at the involved joints are painful
- No soft tissue edema
- No crepitus



Extra Articular Manifestations :

- No Ocular manifestations ( episcleritis , scleritis , keratoconjunctivitis sicca )
- No hearing loss
- No muscle atrophy
- No xerostomia , parotid gland enlargement  , dysphagia
- No lymphadenopathy 

Systemic Examination:

CVS :

- Apex beat at 5th intercostal space medial to midclavicular line
- S1 & S2 heard
- No Murmurs
- Normal JVP

RS :

- Normal Vesicular Breath Sounds are heard
- No added sounds

CNS :

- Sensations are preserved 
- Joint position sense is intact
- Gait is normal
- Cranial nerves are intact
- Reflexes are preserved

ABDOMEN :

- No abnormal findings found

Investigations :

1. Complete blood picture


2. ESR : Elevated


3. CRP : Elevated 


4. Rheumatoid factor :- Positive
5. Anti Cyclic Citrullinated Peptides ( CCP ) :- Negative


6. Liver Function tests


7. Urine examination


8. X - ray



Provisional Diagnosis :

Rheumatoid Arthritis

DIAGNOSIS OF RHEUMATOID ARTHRITIS:- 


EUROPEAN LEAGUE AGAINST RHEUMATISM CRITERIA (EULAR)


* Score Greater than 6 is suggestive of Definite Rheumatoid Arthritis *


Criterion.                                                      

Score

JOINTS AFFECTED


1 large joint

0        

2-10 large joints

1

1-3 small joints                                          

2

4-10 small joints

3

>10 joints

5

SEROLOGY


Negative RF and ACPA.                                     

0

Low positive

2

High positive

3

DURATION OF SYMPTOMS


<6weeks

0

>6weeks

1

ACUTE PHASE REACTANTS


Normal CRP and ESR

0

Abnormal

1


Here , 

A. Joints Affected :
Involvement of MCP Joints of both hands - Score of  2

B. Serology :
Rheumatoid Factor is Highly Positive - Score of  3

C. Acute Phase Reactants :
Abnormal ESR & CRP - Score of  1

D. Duration of Symptoms :
More than 6 weeks - Score of  1

TOTAL SCORE - 2 + 3 + 1 + 1 = 7 ( which is more than 6 )

Treatment :

1. Methyl prednisolone


2. Hydrocortisone 


3. Tramadol hydrochloride 


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